A Comparative Study on Haematological Changes before and One hour after Haemodialysis in Patients with End Stage Renal Disease

Introduction: Normal kidney function is very important for maintaining homeostasis. Any deviation of normal renal leads to End-stage disease (ESRD) the last stage chronic (CKD) resulting from different aetiologies. Different haematological abnormalities in patients with ESRD result multiple pathogenesis. Treatment this condition requires multidisciplinary approach. Among all treatment options haemodialysis (HD) most common, widely accepted and available option. Objective: To find out effectiveness improvement deviations developed during course ESRD. Materials Methods: A total 72 both sexes age ranging 25 years 70 were included comparative cross sectional study carried Combined Military Hospital Armed Forces Institute Pathology, Dhaka Cantonment November 2014 October 2015. Results: The pre dialysis parameters found TRBC: 3.4 ± 0.5 X 1012/L, haemoglobin (Hb) level : 9.5 1.4 gm/dL, Haematocrit (HCT): 29.1 4.4%, Mean corpuscular volume (MCV): 83.5 7 fl, Hb (MCH): 28 1.8 pg, concentration (MCHC): 31.0 2.9 gm/dl, Total leucocyte count (TLC): 6.6 1.9 X109/L, Neutrophil: 66.3 7.8 %, Lymphocyte: 24.5 6.9 Monocyte: 5.0 1.8%, Eosinophil: 4.1 2.4 Platelet: 184.3 66.5 109/L. One hour post HD values are: 3.6 0.6 X1012/L, level:10.1 1.6 Hct: 30.9 5 MCV:82.6 MCH: 2.3 MCHC: 32.2 gm/dl,TLC: 7.3 109/L, 69.2 21.6 5.5 5.3 2 3.9 2.3%. 206.1 63.6 X109/L. these TRBC, level, Hct, MCH, MCHC, TLC, Neutrophil, Lymphocyte Platelet significantly improved after (p value < .05). Conclusion: Haemodialysis management CKD/ESRD played a pivotal role improving deranged by conditions. JAFMC Bangladesh. Vol 18, No 1 (June) 2022: 39-42